I have been to St. Louis several times, but still never the A-B thing.
However I have been to Grant's Farm, where they serve a pint to every adult with your admission, and it's a nice big zoo kind of thing including the legendary Clydesdales.
There's a lot of great breweries and I haven't seen them all yet. I liked Schlafly's and Square One, still need to see some more. Maybe after your trip you can let us know which ones are worth a visit.
Also, I need to say that whether you have kids or are a kid at heart, you really need to see the City Museum... which is a misnomer because it's really not a museum at all, but like an enormous fun house with a million little secret passageways and mazes and nooks & crannies to crawl through and run around and just have an amazing time. I'm childish enough that at age 40, I would go there all by myself and run around like I was 6 years old and just have a great time. Must be seen to be believed!