It can be done, but it's not easy. Having a brew partner is vital, and it all depends on how good you are on crutches. I have had a multitude of surgeries that required crutch time, so I got good on them.
Recently ruptured my achilles tendon, and I still managed to brew a batch. It wasn't easy, but it was sorta therapeutic, reminding me that life does indeed go on. Depending on your setup (mine is in my basement, so once I can handle stairs I'm golden), getting a chair or two and a small table setup can make this a doable thing. Lifting was tough to do while balancing, but I rested the leg on a chair and used leverage to help get the job done. It's not easy, so take it easy, but if you are wondering about plausibility, it's doable